Faculty Directory|
Panagiotis A. Tsonis Director, Center for Tissue Regeneration and Engineering at Dayton (TREND) Office/Lab: SC373A/46
Phone: (937) 229-2579/2565 Fax: (937) 229-2021 Email: Panagiotis A. Tsonis Curriculum Vitae Check out my course, BIO462/594 |
Research: Mechanisms and induction of tissue regeneration Tissue repair and regeneration of body parts are quite amazing biological and physiological processes that occur in all animals to one degree or another. Many animals, including humans, contain stem cells or progenitor cells that are capable of differentiating to several cell types at injury sites and contribute to repair. On the other hand some urodele amphibians have the incredible capacity of regenerating whole body parts, such as limbs, tails, spinal cord, eyes, brain, ear, jaw and heart. In these animals regeneration is achieved through the dedifferentiation of the existing terminally differentiated cells at the injury site. In other words these animals possess the unique capacity of returning their adult somatic cells back to an embryonic state or a progenitor state. To address these very important questions we use as a system regeneration of eye and limb tissues in amphibians. During the past few years we have learned much about the induction mechanisms and we are attempting to extend our studies in mammals as well.
Regenerative Biology
Gene Regulation and Expression
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